How to Set Up Your ResMed AirSense 11 for the First Time

June 20, 2025
4:56 am

The ResMed AirSense 11 AutoSet CPAP Machine is a powerful tool designed to help individuals manage sleep apnea effectively. If you’ve just received your device, congratulations, you’re on your way to better sleep and improved health. This guide will walk you through the setup process and answer the most common questions about using, adjusting, and maintaining your machine. Whether you’re exploring CPAP therapy for the first time or upgrading from an older model, we’ll help you feel confident from the start. Plus, we’ll point out where to find reliable supplies and expert guidance like at cpapRX.

What’s Inside the Box?

When you unbox your AirSense 11, you’ll find:

The AirSense 11 AutoSet CPAP device
Integrated HumidAir humidifier
Tubing (standard or heated)
Power supply and cable
A user manual and quick-start materials
One disposable filter (already installed)

Before powering up, double-check that all items are present and undamaged. If you need any extras or prefer to have a backup on hand, cpapRX offers all the replacement parts and accessories you might need.

Step-by-Step: Setting Up Your AirSense 11

1. Connect the Components

Plug the power supply into the machine and then into an outlet.
Attach the tubing to device through the air outlet.
Fill the water chamber with distilled water and follow this by inserting it into the side of the machine.
Secure the CPAP mask to the opposite end of the tubing.

2. Power On the Device

Turn the machine on using the Start/Stop button. The AirSense 11’s touchscreen will guide you through connecting to the myAir app, which tracks your progress and gives personalized tips.

Learning the Basics: How to Use the ResMed AirSense 11

Daily use is straightforward:

Ensure your mask is securely on before starting the device.
Tap the Start/Stop button or simply begin breathing to activate the auto-start feature.
The machine will automatically adjust the air pressure throughout the night based on your needs.

How to Adjust the AirSense 11 Humidifier for Comfort

Humidity levels are adjustable to enhance your comfort. Here’s how:

From the main menu, tap “My Options.”
Choose “Humidity Level.”
Use the slider to set it anywhere from 0 (off) to 8 (highest moisture).

This feature is especially useful if you experience nasal dryness or throat irritation. If you notice condensation forming in the tubing, try turning the humidity down slightly.

How to Turn Off the Humidifier on the AirSense 11

Some users prefer to sleep without added moisture or need to travel without distilled water. To deactivate the humidifier:

Go to My Options, then Climate Control.
Switch Climate Control to Manual.
Set the Humidity Level to 0.

Cleaning Your AirSense 11: A Weekly Routine

Keeping your CPAP equipment clean is important for longevity, hygiene and performance.

Daily:

Rinse the humidifier chamber with warm water and let it air dry.

Weekly:

Wash the water chamber, mask, and tubing in warm, soapy water.
Rinse thoroughly & hang it or lay it flat to air dry.
Wipe the machine with a soft, damp cloth.

Avoid harsh chemicals. For added convenience, cpapRX carries specially formulated cleaning solutions and wipes for CPAP equipment.

Replacing the Air Filter on the ResMed AirSense 11

The air filter prevents dust and allergens from entering your machine. Over time, it will need to be replaced. Here’s how:

Find the filter cover on the side of the unit.
Remove the old filter – do not wash or reuse.
Insert a new filter and snap the cover back in place.

Filters should typically be changed every month or two. You can easily stock up on multi-pack filters at cpapRX.

Adjusting Pressure Settings on Your ResMed CPAP Machine

The AirSense 11 AutoSet adjusts pressure automatically. However, if your sleep specialist recommends a fixed range, you may need to modify the settings.
Important: Only adjust pressure settings under medical supervision.
To make changes:

Enter the clinical menu (hold the Home and Dial buttons for a few seconds).
Navigate to Pressure Settings.
Adjust the min and max pressure according to your provider’s instructions.

If you need help understanding your pressure requirements, cpapRX offers consultations with licensed sleep experts.

Common Questions and Quick Fixes

Dry mouth or congestion? Try raising the humidity level or switching to a heated hose.
Device feels noisy? Check that the tubing and water chamber are sealed tightly.
Pressure too high or low? Talk to a doctor or connect with a cpapRX support for further guidance.

Why Trust cpapRX?

Choosing the right equipment is only part of your CPAP journey. Support and reliability matter just as much. At cpapRX, you’ll find:

Certified ResMed products
A knowledgeable clinical team
Hassle-free ordering of supplies
Fast delivery and refill options

Whether you’re purchasing your first machine or just need filters and replacement masks, cpapRX has you covered with quality gear and expert advice. Setting up your ResMed AirSense 11 CPAP Machine for the first time doesn’t have to be overwhelming. Once everything is in place, nightly use becomes second nature—and the improvements to your sleep and overall health are well worth the effort. Need supplies, filters, or help with your setup? Visit cpapRX.com to find everything you need to make your CPAP therapy comfortable and effective from night one.

FAQs

What are the key features of the ResMed AirSense 11 AutoSet CPAP Machine?

The AirSense 11 AutoSet includes an integrated humidifier, advanced AutoSet algorithm, touchscreen display, built-in Bluetooth, Wi-Fi connectivity, and access to the ResMed myAir™ app for real-time sleep therapy tracking. It also supports both CPAP and APAP modes.

Does the AirSense 11 AutoSet come with a built-in humidifier?

Yes, the ResMed AirSense 11 AutoSet includes a built-in heated humidifier designed to reduce dryness and improve comfort. It also offers Climate Control features when paired with a heated tube.

How much does the ResMed AirSense 11 AutoSet CPAP Machine cost?

The price of the AirSense 11 AutoSet typically ranges from $899 to $1,198 in the U.S., depending on the provider, included accessories, and warranty options.

What is the difference between AirSense 11 and AirSense 10?

The AirSense 11 features a modern touchscreen interface, enhanced Bluetooth/Wi-Fi connectivity, and access to the myAir app. Compared to the AirSense 10, it offers improved usability and software updates, though both provide high-quality auto-adjusting CPAP therapy.

Is the ResMed AirSense 11 AutoSet worth the upgrade from older models?

Yes. For users who value a user-friendly interface, remote updates, and therapy tracking via smartphone, the AirSense 11 AutoSet offers significant improvements. It’s especially useful for new users or those seeking the latest in CPAP technology.

About
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Anjini Badhey

Content Writer at Bizionic Technologies

I am a dedicated health writer with a passion for creating informative and engaging content that empowers readers to take control of their health. I believe that the right information can transform lives, and I’m committed to helping individuals better understand their options, stay informed about the latest in sleep apnea technology, and feel supported in their journey toward better sleep. My goal is to write with purpose, empathy, and clarity, making a meaningful impact one article at a time.

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